Description
β--lactamase inactivates β-lactam antibiotics by breaking open the β-lactam ring.
Abbr
β-Lactamase, Native (Bacillus cereus)
Source
Bacillus cereus 569/H9
Applications
Useful for assaying penicillins and cephalosporins.
Enzyme Commission Number
EC 3.5.2.6
Unit Definition
One unit is defined as the amount of enzyme that will hydrolyze 1.0 µmol benzyl penicillin and 1.0 µmol of cephalosporin C, respectively, per min at 25°C.
Storage
at -20°C. Ok to freeze.
Preparation Instructions
Following reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 1 month at 4°C.
Synonyms
β-lactamase; penicillinase; cephalosporinase; neutrapen; penicillin β-lactamase; exopenicillinase; ampicillinase; penicillin amido-β-lactamhydrolase; penicillinase I, II; β-lactamase I-III; β-lactamase A, B, C; β-lactamase AME I; cephalosporin-β-lactamase; EC 3.5.2.6; 9073-60-3
