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Topoisomerase I from Human, Recombinant

Cat No.
NATE-1340
Description
Topoisomerase I relaxes supercoiled DNA molecules. The enzyme initiates transient breakages and rejoins of phosphodiester bonds in superhelical turns of closed-circular DNA. Enzyme activity is independent of right-and left-handed superhelices.
Abbr
TOPO I, Recombinant (Human)
Alias
TOPO I
Source
Baculovirus-infected insect cells (Spodoptera frugiperda)
Species
Human
Concentration
10 U/μl
Stability
Stable for 3 months undiluted
Storage
Store at -80°C. It is recommended that the enzyme is aliquoted to avoid repeated freeze-thaw cycles.
Synonyms
Topoisomerase I; EC 5.99.1.2; type I DNA topoisomerase; untwisting enzyme; relaxing enzyme; nicking-closing enzyme; swivelase; ω-protein; deoxyribonucleate topoisomerase; topoisomerase; type I DNA topoisomerase; DNA topoisomerase; TOPO I
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