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(+)-α-santalene synthase [(2Z,6Z)-farnesyl diphosphate cyclizing]

Cat No.
EXWM-5210
Description
The enzyme synthesizes a mixture of sesquiterpenoids from (2Z,6Z)-farnesyl diphosphate. Following dephosphorylation of (2Z,6Z)-farnesyl diphosphate, the (2Z,6Z)-farnesyl carbocation is converted to either the (6R)- or the (6S)-bisabolyl cations depending on the stereochemistry of the 6,1 closure. The (6R)-bisabolyl cation will then lead to the formation of (+)-α-santalene (EC 4.2.3.50), while the (6S)-bisabolyl cation will give rise to (+)-endo-β-bergamotene (see EC 4.2.3.53) as well as (-)-endo-α-bergamotene (see EC 4.2.3.54). Small amounts of (-)-epi-β-santalene are also formed from the (6R)-bisabolyl cation and small amounts of (-)-exo-α-bergamotene are formed from the (6S)-bisabolyl cation.
Form
Liquid or lyophilized powder
Enzyme Commission Number
Storage
Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC.
Synonyms
SBS (ambiguous)
Reaction
(2Z,6Z)-farnesyl diphosphate = (+)-α-santalene + diphosphate
Notes
This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.

Our Products Cannot Be Used As Medicines Directly For Personal Use.

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