Products

Enzymes for Research, Diagnostic and Industrial Use

5'-Nucleotidase from Human, Recombinant


Cat No.
NATE-0795
Description
5'-nucleotidase is an extracellular enzyme that converts nucleoside-5'−monophosphates to nucleosides with a substrate preference of AMP. Native 5'-nucleotidase is a GPI-anchored protein whose exporession is upregulated by hypoxia. 5'-nucleotidase has many functions in vivo including the generation of extracellular adenosine. 5'-Nucleotidase has various clinical significances. It is a key molecule in the regulation of cancer cells proliferation, migration and invasion in vitro tumor angiogenesis, and tumor immune escape in vivo. Due to this important role, the enzyme is a potential target for cancer research.1 It is also involved in salvage of extracellular nucleotides and plays a key role in the control of tissue homeostasis.
Abbr
AMPase, Recombinant (Human)
Alias
AMPase; UMPase; CD73; NT5E
Source
CHO cells
Species
Human
Package
vial of 6-12 μg
Form
Supplied as a solution containing Tris, NaCl, CaCl2, and 20% glycerol.
Enzyme Commission Number
EC 3.1.3.5
Activity
>15 U/mg
CAS No.
9027-73-0
Molecular Weight
~61 kDa by SDS-PAGE (reducing)
Purity
>90% (SDS-PAGE)
Unit Definition
One unit will hydrolyze 1.0 μmole of inorganic phosphorus from adenosine 5'-monophosphate per min at pH 9.0 at 37 °C.
Storage
Store at -70°C
Synonyms
uridine 5'-nucleotidase; 5'-adenylic phosphatase; adenosine 5'-phosphatase; AMP phosphatase; adenosine monophosphatase; 5'-mononucleotidase; AMPase; UMPase; snake venom 5'-nucleotidase; thimidine monophosphate nucleotidase; 5'-AMPase; 5'-AMP nucleotidase; AMP phosphohydrolase; IMP 5'-nucleotidase; EC 3.1.3.5; CD73; NT5E; ecto-5'-nucleotidase
Download Datasheet:
SDS:


“AMPase” Total Products Page

Inquiry
Related Products
Catalog
Product Name
EC No.
CAS No.
Source
Price
CatalogNATE-1717
EC No.EC 3.1.3.5
CAS No.9027-73-0
SourceMicroorganism
CatalogNATE-1742
EC No.EC 3.1.3.5
CAS No.9027-73-0
SourceHuman
CatalogNATE-0072
EC No.EC 3.1.3.5
CAS No.9027-73-0
SourceCrotalus atrox
CatalogEXWM-3654
ProductName5'-nucleotidase
EC No.EC 3.1.3.5
CAS No.9027-73-0
Source
+ See More >>
Related Services
Online Inquiry
Name:
*Phone:
*E-mail Address:
Country or Region:
Company/Institution:
*Products or Services of Interest:
Quantity:
Project Description:
Our products are not intended for direct clinical use!
*Verification Code:
Verification code

Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.


Sitemap | Privacy Policy | Terms and Conditions
Copyright ©2011 - 2021 Creative Enzymes.
Contact Us 45-1 Ramsey Road, Shirley, NY 11967, USA
Email: info@creative-enzymes.com
Tel: 1-631-562-8517 1-516-512-3133
Fax: 1-631-938-8127
Distributors To view the contact information for a specific location, select the desired country or region:
     
0
Click unfold / close
Inquiry Basket
Delete selected Check Out
Decide to move out of the shopping cart??

Sure No, Back
 

Please choose product!

< Go Back
You have already added to buy this product