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Enzymes for Research, Diagnostic and Industrial Use

Everolimus (RAD001)

Cat No.
CEI-0122
Description
Everolimus (RAD001) can inhibit FKBP12 with IC50 of 1.6-2.4 nM.
Alias
Certican, Zortress, Afinitor
CAS No.
159351-69-6
Molecular Weight
958.22
Purity
>99%
Storage
2 years at -20centigrade Powder
Synonyms
Certican, Zortress, Afinitor
Targets
mTOR
Molecular Formula
C53H83NO14
Chemical Name
23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine, rapamycin deriv
Solubility
DMSO 30 mg/mL Water
In vitro
As an mTOR inhibitor, everolimus (RAD001) can FKBP12 with IC50 of 1.6-2.4 nM. RAD001 inhibits tumor cell growth directly, blocks angiogenesis, and suppresses the immune response.
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