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Heparinase I from Flavobacterium heparinum, Recombinant
Cat No.
NATE-1946
Description
Heparin-degrading lyase that recognizes heparin sulfate proteoglycan as its primary substrate. Heparinase I and III plays vital role in various biological processes: modulate cell-growth factor interactions, cell-lipoprotein interactions, neovascularization. It cleaves highly sulphated polysaccharide chains in presence of 2-O-sulfated α-L-idopyranosyluronic acid and β-D-glucopyranosyluronic acid residues of polysaccharides.
Source
E.coli
Species
Flavobacterium heparinum
Form
Powder
Enzyme Commission Number
EC 4.2.2.7
Activity
~ 100IU/mg
CAS No.
9025-39-2
Specificity
Heparin; heparan sulfate (specific activity with heparin is approx. 3 times higher than with heparan sulfate).
Unit Definition
One international unit (IU) of recombinant heparinase I is defined as the amount of enzyme that will liberate 1.0 μmole unsaturated oligosaccharides from porcine mucosal heparin per minute at 35 °C and pH 7.0.
Stability
Expiration of heparinase I is 12 months from manufacturing date, frozen at -96 to -20 °C in PBS.
Synonyms
Heparinase; Heparin lyase; Heparin eliminase; Heparin-sulfate lyase; Heparin-sulfate eliminase; Heparitin-sulfate lyase; Heparinase I
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Download Datasheet"Heparinase" Total Products Page
| Catalog | Product Name | EC No. | CAS No. | Source | Price |
|---|---|---|---|---|---|
| NATE-1948 | Heparinase III from Flavobacterium heparinum, Recombinant | EC 4.2.2.8 | 37290-86-1 | E.coli | Inquiry |
| NATE-1947 | Heparinase II from Flavobacterium heparinum, Recombinant | 149371-12-0 | E.coli | Inquiry | |
| NATE-0337 | Native Flavobacterium heparinum Heparinase I and III Blend | Flavobacterium heparinum | Inquiry | ||
| NATE-1267 | Heparinase III from Bacteroides eggerthii, Recombinant | 37290-86-1 | E. coli | Inquiry |