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Enzymes for Research, Diagnostic and Industrial Use

Imiquimod


Cat No.
LIGC-006
Description
Imiquimod is a caspase 3 activator, which directly induces procaspase 3 cleavage to active caspase 3. Imiquimod induces apoptosis in vivo in basal cell carcinoma. Its anti-tumor activity is related to the induction of apoptosis. Imiquimod has anti-angiogenic, anti-inflammatory, anti-viral activities. Imiquimod also acts as an immune response modulator inducing the secretion of various cytokines and chemokines.
Applications
An immune response modifier. It stimulates the production of interferon-a.
Appearance
Off-White Solid
CAS No.
99011-02-6
Molecular Weight
240.3
Purity
>95 %
Stability
Stable for at least 2 years when stored at -20°C.
Storage
Store at -20°C.
Synonyms
Aldara; Beselna; R-837; TMX 101; Zyclara
Molecular Formula
C14H16N4
Melting Point
292-294°C
Solubility
Soluble to 5 mM in DMSO with gentle warming
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