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Enzymes for Research, Diagnostic and Industrial Use

Marimastat

Cat No.
CEI-0575
Description
A broad spectrum matrix metalloprotease (MMP) inhibitor with IC50 values of 3, 5, 6, 9 and 13 nM for MMP-9, MMP-1, MMP-2, MMP-14 and MMP-7 respectively. It covalently binds to the zinc(II) ion in the active site of MMPs, thereby inhibiting the action of MMPs, inducing extracellular matrix degradation, and inhibiting angiogenesis, tumor growth and invasion, and metastasis.
Alias
BB-2516; TA-2516; Marimistat
Appearance
White crystalline solid
Product Overview
A broad spectrum MMP inhibitor
CAS No.
154039-60-8
Molecular Weight
357.41
Purity
>99% by HPLC
Storage
-20 centigrade
Synonyms
BB-2516; TA-2516; Marimistat
Targets
MPTP
Molecular Formula
C₁₅H₂₉N₃O₅
Chemical Name
(2S,3R)-N4-[(1S)-2,2-Dimethyl-1-[(-[(methylamino)carbonyl]propyl]-N1,2-dihydroxy-3-(2-methylpropyl)butanediamide
Solubility
DMSO (25 mg/ml) or H2O (20 mg/ml)
Shipping Conditions
RT
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