Description
Transketolase is highly specific for ketol donor substrates and is stereospecific and enantioselective to hydroxyaldehyde substrates with an (R) configuration. It specifically catalyzes the irreversible transfer of one ketol unit from α-hydroxypyruvic acid to an aldehyde to produce a D-threo (3S,4R)ketose.
Abbr
Transketolase, Native (E. coli)
Applications
Transketolase is widely used in organic synthesis.
Enzyme Commission Number
EC 2.2.1.1
Unit Definition
1 U corresponds to the amount of enzyme which will produce 1 μmol of glyceraldehyde-3-phosphate from xylulose-5-phosphate per minute at pH 7.7 and 25°C, in the presence of ribose-5-phosphate, thiamine pyrophosphate and Mg2+
Synonyms
Transketolase; EC 2.2.1.1; 9014-48-6; glycolaldehydetransferase; Glycolaldehyde Transferase
