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Enzymes for Research, Diagnostic and Industrial Use

PX-866

Cat No.
CEI-0972
Description
Inhibits PI3-kinase with selectivity for p110alpha (IC50=0.1 nM). Displays antitumor activity. Irreversible. Cell permeable.
Abbr
PX-866(PIK3CA)
Alias
(1E, 4S, 4aR, 5R, 6aS, 9aR)-5-(acetyloxy)-1-[(di-2-propen-1-ylamino) methylene]-4, 4a, 5, 6, 6a, 8, 9, 9-a-octahydro-11-hydroxy-4-(methoxymethyl)-4a, 6a-dimethyl-cyclopenta [5, 6] naphtha [1, 2-c] pyran-2, 7, 10(1H)-trione
Appearance
Orange powder
Product Overview
PI3K inhibitor
CAS No.
502632-66-8
Molecular Weight
525.6
Purity
>98% (TLC); NMR (Conforms)
Synonyms
(1E,4S,4aR,5R,6aS,9aR)-5-(acetyloxy)-1-[(di-2-propen-1-ylamino) methylene]-4,4a,5,6,6a,8,9,9-a-octahydro-11-hydroxy-4-(methoxymethyl)-4a,6a-dimethyl-cyclopenta [5,6] naphtha [1,2-c] pyran-2,7,10(1H)-trione
Targets
PI3K
Molecular Formula
C29H35NO8
Solubility
May be dissolved in DMSO (25 mg/ml)
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