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Enzymes for Research, Diagnostic and Industrial Use

retinoid isomerohydrolase

Cat No.
EXWM-3492
Description
This enzyme, which operates in the retinal pigment epithelium (RPE), catalyses the cleavage and isomerization of all-trans-retinyl fatty acid esters to 11-cis-retinol, a key step in the regeneration of the visual chromophore in the vertebrate visual cycle. Interaction of the enzyme with the membrane is critical for its enzymic activity.
Form
Liquid or lyophilized powder
Enzyme Commission Number
CAS No.
106389-24-6
Storage
Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC.
Synonyms
all-trans-retinyl-palmitate hydrolase (ambiguous); retinol isomerase (ambiguous); all-trans-retinol isomerase:hydrolase (ambiguous); all-trans-retinylester 11-cis isomerohydrolase; RPE65 (gene name)
Reaction
an all-trans-retinyl ester + H2O = 11-cis-retinol + a fatty acid
Notes
This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
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