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Enzymes for Research, Diagnostic and Industrial Use

SD169

Cat No.
CEI-1108
Description
SD-169 is an orally available, ATP-competitve, isoenzyme-selective Mitogen-Activated Protein Kinase (MAPK) inhibitor. It is 38 times more potent against p38α MAP kinase (IC50 = 3.2 nM) than p38β MAP kinase (IC50 = 122 nM).
Abbr
SD169(MAPK14)
Alias
RP1-179N16.5, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, P38alpha
Product Overview
ATP-competitve, isoenzyme-selective Mitogen-Activated Protein Kinase (MAPK) inhibitor
CAS No.
1670-87-7
Molecular Weight
160.17
Purity
> 95%
Stability
2 years -20 centigrade Powder
1 month -4 centigrade in DMSO
More than one month -80 centigrade in DMSO
Storage
4 centigrade
Synonyms
RP1-179N16.5, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, P38alpha
Targets
p38α MAP kinase
Molecular Formula
C9H8N2O
Chemical Name
1H-indole-5-carboxamide
Solubility
DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL
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