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COMT

Official Full Name
COMT
Background
Catechol-O-methyltransferase (COMT; EC 2.1.1.6) is one of several enzymes that degrade catecholamines such as dopamine, epinephrine, and norepinephrine. In Humans, catechol-O-methyltransferase protein is encoded by the COMT gene. As the regulation of catecholamines is impaired in a number of medical conditions, several pharmaceutical drugs target COMT to alter its activity and therefore the availability of catecholamines. COMT was first discovered by the biochemist Julius Axelrod in 1957.
Synonyms
catechol O-methyltransferase; COMT; COMT I; COMT II; S-COMT (soluble form of catechol-O-methyltransferase); MB-COMT (membrane-bound form of catechol-O-methyltransferase); catechol methyltransferase; catecholamine O-methyltransferase; EC 2.1.1.6; 9012-25-3; Pyrocatechol-O-methyl Transferase; S-Adenosyl-L-methionine:catechol O-methyltransferase

Catalog
ProductName
EC No.
CAS No.
Source
Price
CatalogEXWM-1961
EC No.EC 2.1.1.6
CAS No.9012-25-3
Source
CatalogNATE-0148
EC No.EC 2.1.1.6
CAS No.9012-25-3
SourcePorcine liver
Related Protocols
CATECHOL O-METHYL TRANSFERASE -Enzymatic Assay Protocol
CATECHOL-O-METHYL TRANSFERASE -Enzymatic Assay Protocol

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