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CTSG

Official Full Name
CTSG
Background
Cathepsin G is an enzymatic protein belonging to the peptidase or protease families. In humans, it is coded by the CTSG gene. The protein encoded by this gene, a member of the peptidase S1 protein family, is found in azurophil granules of neutrophilic polymorphonuclear leukocytes. The encoded protease has a specificity similar to that of chymotrypsin C, but it is most closely related to other immune serine proteases, such as neutrophil elastase and the granzymes. Cathepsin G may participate in the killing and digestion of engulfed pathogens, and in connective tissue remodeling at sites of inflammation. It also localizes to Neutrophil extracellular traps (NETs), via its high affinity for DNA, an unusual property for serine proteases. Transcript variants utilizing alternative polyadenylation signals exist for this gene.
Synonyms
CTSG; cathepsin G; CG; CATG; EC 3.4.21.20; chymotrypsin-like proteinase; neutral proteinase

Catalog
ProductName
EC No.
CAS No.
Source
Price
CatalogEXWM-4120
ProductNamecathepsin G
EC No.EC 3.4.21.20
CAS No.56645-49-9
Source
CatalogNATE-0173
EC No.EC 3.4.21.20
CAS No.56645-49-9
SourceHuman Neutrophi...
CatalogNATE-0175
EC No.EC 3.4.21.20
CAS No.
SourceHuman sputum
CatalogNATE-0174
EC No.EC 3.4.21.20
CAS No.
SourceHuman leukocyte...
Related Protocols
CATHEPSIN G -Enzymatic Assay Protocol
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