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CMA1

Official Full Name
CMA1
Background
Chymases are a family of serine proteases found primarily in mast cells, though also present in basophil granulocytes (e.g. alpha chymase mcpt8). They show broad peptidolytic activity and are involved in a variety of functions. For example, chymases are released by mucosal mast cells upon challenge with parasites and parasite antigens promoting an inflammatory response. Chymases are also known to convert angiotensin I to angiotensin II and thus play a role in hypertension and atherosclerosis. Because of its role in inflammation it has been investigated as a target in the treatment of asthma.
Synonyms
mast cell protease I; skeletal muscle protease; skin chymotryptic proteinase; mast cell serine proteinase# chymase; skeletal muscle (SK) protease; chymase; EC 3.4.21.39; 97501-92-3
Catalog Product Name EC No. CAS No. Source Price
EXWM-4133 chymase EC 3.4.21.39 97501-92-3 Inquiry
NATE-0817 Chymase from Human, Recombinant EC 3.4.21.39 97501-92-3 Pichia pastoris Inquiry