Products

Enzymes for Research, Diagnostic and Industrial Use

β-Lapachone

Cat No.
CEI-0468
Description
Cell-permeable. A DNA topoisomerase I inhibitor. Unlike Camptothecin, β-lapachone does not stabilize the cleavable complex, indicating a novel mode of action. Induces apoptosis in HL-60 and human prostate cancer cells via a p53-independent mechanism and blocks the cell cycle at G0/G1. Also acts as a histone demethylase inhibitor selective to JMJ2DE (IC50 =3.6 µM).
Appearance
White solid
Product Overview
A DNA topoisomerase I inhibitor and a histone demethylase (HDM) inhibitor
CAS No.
4707-32-8
Molecular Weight
435.52
Purity
>98% by TLC
Storage
-20 centigrade
Targets
TOP1MT
Molecular Formula
C15H14O3
Chemical Name
3,4-Dihydro-2,2-dimethyl-2H-naphtho­[1,2-b]pyran-5,6-dione
Solubility
DMSO (~ 25 mg/ml)
Shipping Conditions
Gel pack
Download Datasheet:



Inquiry
Realted Products
Catalog
ProductName
EC No.
CAS No.
Source
Price
CatalogCEI-0301
ProductNameTopotecan HCl
EC No.
CAS No.119413-54-6
Source
CatalogCEI-0467
EC No.
CAS No.100286-90-6
Source
CatalogCEI-0681
ProductNameCamptothecin
EC No.
CAS No.7689-03-4
Source
Online Inquiry
Name:
*Phone:
*E-mail Address:
Country:
Company/Institution:
*Products or Services Interested:
Quantity:
Project Description:
Our Products are Not Intended for Private Therapeutic Use!
*Verification Code:
Please input "enzymes"(case insensitive) as verification code.

Welcome! For price inquiries, please feel free to contact us through the form below through the form on the left side. We will get back to you as soon as possible.

Sitemap  Privacy Policy
Copyright ©2011 - 2017 Creative Enzymes.
Contact Us 45-1 Ramsey Road, Shirley, NY 11967, USA
Email: info@creative-enzymes.com
Tel: 1-631-562-8517 1-631-448-7888
Fax: 1-631-938-8127
Distributors To view the contact information for a specific location, select the desired country: