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α-N-Acetylgalactosaminidase from Chryseobacterium meningosepticum, Recombinant

Cat No.
NATE-1259
Description
α-N-acetylgalactosaminidase (EC 3.2.1.49) is a glycoside hydrolase from bacteria and animals, also known as nagalase. The human gene that codes for this enzyme is NAGA. Mutations in this gene and the deficiency in alpha-N-acetylgalactosaminidase activity have been identified as the cause of Schindler disease.
Abbr
α-NAGA, Recombinant (Chryseobacterium meningosepticum)
Alias
α-NAGA
Source
E. coli
Species
Chryseobacterium meningosepticum
Molecular Weight
47 kDa
Concentration
20,000 units/ml
Unit Definition
One unit is defined as the amount of enzyme required to cleave > 95% of the terminal α-D-N-acetylgalactosamine from 1 nmol (GalNAcα1-3)(Fucα1-2)Galβ1-4Glc-7-amino-4-methyl-coumarin (AMC), in 1 hour at 37°C in a total reaction volume of 10 µl.
Storage
at -20°C
Synonyms
EC 3.2.1.49; α-N-acetylgalactosaminidase; Alpha-N-acetylgalactosaminidase; α-acetylgalactosaminidase; N-acetyl-α-D-galactosaminidase; N-acetyl-α-galactosaminidase; α-NAGAL; α-NAGA; α-GalNAcase
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