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17-DMAG hydrochloride

Cat No.
CEI-0535
Description
A water-soluble analog of 17-AAG that displays better stability and low in vivo toxicity similar to 17-AAG, but undergoes limited metabolism compared to 17-AAG. Binds specifically to heat shock protein90 (Hsp90) in a manner similar to geldanamycin.
Alias
Alvespimycin
Appearance
White to off-white solid
Product Overview
A Hsp90 inhibitor
CAS No.
467214-21-7
Molecular Weight
386.42
Purity
>95% by HPLC
Storage
-20 centigrade
Synonyms
Alvespimycin
Targets
HSP90
Molecular Formula
C₃₂H₄₈N₄O₈•HCl
Chemical Name
17-(Dimethylaminoethylamino)-17-demethoxygeldanamycin Hydrochloride
Solubility
DMSO (20 mM)
Shipping Conditions
Gel pack
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