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Enzymes for Research, Diagnostic and Industrial Use

Biotin-DEVD-FMK

Cat No.
CEI-0431
Description
A synthetic peptide that irreversibly inhibits activity of caspase-3 and related caspases and blocks apoptosis. The inhibitor is designed as a methyl ester to enhance cell permeability. The conjugation with biotin allows detection of activated caspases in conjunction with avidin-tags. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups).
Alias
Biotin-DEVD-FMK, DEVD-FMK, Biotin-
Appearance
White to off-white solid
Product Overview
A caspase-3 inhibitor
Molecular Weight
189.21
Purity
>99% by TLC
Storage
-20 centigrade
Synonyms
Biotin-DEVD-FMK, DEVD-FMK, Biotin-
Targets
caspase-3
Molecular Formula
C₃₈H₆₀FN₇O₁₃S
Solubility
DMSO (~25 mg/ml) or EtOH (~25 mg/ml)
Shipping Conditions
Gel pack
Amino Acid Sequence
Biotin-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-FMK
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