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Enzymes for Research, Diagnostic and Industrial Use

Biotin-VAD-FMK

Cat No.
CEI-0420
Description
A synthetic peptide that irreversibly inhibits activity of caspase family proteases and blocks apoptosis. The inhibitor is designed as a methyl ester to enhance cell permeability. The conjugation with biotin allows detection of activated caspases in conjunction with avidin-tags. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups).
Alias
Biotin-VAD-FMK, VAD-FMK, Biotin-
Appearance
White solid
Product Overview
A pan-caspase inhibitor
Molecular Weight
390.41
Purity
>98% by HPLC
Storage
RT
Synonyms
Biotin-VAD-FMK, VAD-FMK, Biotin-
Targets
caspase
Molecular Formula
C₃₀H₄₉FN₆O₈S
Solubility
DMSO (~10 mg/ml) or Ethanol (<1 mg/ml)
Shipping Conditions
Gel pack
Amino Acid Sequence
Biotin-Val-Ala-Asp(OMe)-FMK
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