Description
Enteropeptidase (also called enterokinase) is an enzyme produced by cells of the duodenum and involved in human and animal digestion. It is secreted from intestinal glands (the crypts of Lieberkühn) following the entry of ingested food passing from the stomach. Enteropeptidase converts trypsinogen (a zymogen) into its active form trypsin, resulting in the subsequent activation of pancreatic digestive enzymes. Absence of enteropeptidase results in intestinal digestion impairment.
Abbr
Enterokinase, Recombinant (Human)
Product Overview
> 90% (SDS-PAGE), > 90% (HPLC), cell culture tested
Form
Lyophilized from 10 mM Sodium Phosphate, pH 7.5 + 1 mM Calcium Chloride.
Enzyme Commission Number
EC 3.4.21.9
Activity
Type I, > 20 units/mg protein
Molecular Weight
108.7 kDa
Buffer
Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to store in working aliquots at-20°C to-80°C.
Function
peptidase activity; scavenger receptor activity; serine-type endopeptidase activity
Synonyms
enterokinase; enteropeptidase; EC 3.4.21.9; 9014-74-8
