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Epoxomicin

Cat No.
CEI-0627
Description
Originally isolated from Actinomycetes strain based on its potent in vivo antitumor activity, Epoxomicin is a potent, cell-permeable, selective and irreversible proteasome inhibitor. More potent inhibitor of the chymotrypsin-like activity of the proteasome than Lactacystin. Blocks also trypsin-like and PGPH activities of the proteasome.
Alias
BU-4061T
Appearance
Off-white solid
Product Overview
A potent proteasome inhibitor
CAS No.
134381-21-8
Molecular Weight
248.23
Purity
~80% by TLC
Storage
-20 centigrade
Synonyms
BU-4061T
Targets
Proteasome
Molecular Formula
C28H50N4O7
Chemical Name
N-​acetyl-​N-​methyl-​L-​isoleucyl-​L-​isoleucyl-​N-​[(1S)-​3-​methyl-​ 1-​[[(2R)-​2-​methyloxiranyl]carbonyl]butyl]-​L-​threoninamide
Solubility
H₂O (200 mg/ml) or MeOH (50 mg/ml)
Shipping Conditions
Gel pack
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