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GNE-490

Cat No.
CEI-1121
Description
GNE-490 is a highly selective pan-PI3K inhibitor and demonstrates selectivity over mTOR. It has good pharmacokinetic (PK) parameters and demonstrates knock down of pathway markers in vivo. This compound represents an excellent tool to further evaluate the therapeutic potential of a PI3K inhibitor in the treatment of cancer.
Abbr
GNE-490(pan-PI3K )
Product Overview
pan-PI3K inhibitor
CAS No.
1033739-92-2
Molecular Weight
386.47
Purity
> 95%
Stability
2 years -20 centigrade Powder
1 month -4 centigrade in DMSO
More than one month -80 centigrade in DMSO
Storage
-20 centigrade
Targets
pan-PI3K
Molecular Formula
C18H22N6O2S
Chemical Name
2-(2-(2-amino-4-methylpyrimidin-5-yl)-4-morpholinothieno[3,2-d]pyrimidin-6-yl)propan-2-ol
Solubility
DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL
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CAS No.1033735-94-2
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