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histidine ammonia-lyase
Cat No.
EXWM-5289
Description
This enzyme is a member of the aromatic amino acid lyase family, other members of which are EC 4.3.1.23 (tyrosine ammonia-lyase), EC 4.3.1.24 (phenylalanine ammonia-lyase) and EC 4.3.1.25 (phenylalanine/tyrosine ammonia-lyase). The enzyme contains the cofactor 3,5-dihydro-5-methylidene-4H-imidazol-4-one (MIO), which is common to this family. This unique cofactor is formed autocatalytically by cyclization and dehydration of the three amino-acid residues alanine, serine and glycine. This enzyme catalyses the first step in the degradation of histidine and the product, urocanic acid, is further metabolized to glutamate.
Form
Liquid or lyophilized powder
Enzyme Commission Number
CAS No.
9013-75-6
Storage
Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.
Synonyms
histidase; histidinase; histidine α-deaminase; L-histidine ammonia-lyase
Reaction
L-histidine = urocanate + NH3
Notes
This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
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