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Enzymes for Research, Diagnostic and Industrial Use

homospermidine synthase (spermidine-specific)

Cat No.
EXWM-2781
Description
The reaction of this enzyme occurs in three steps, with some of the intermediates presumably remaining enzyme-bound: (a) NAD+-dependent dehydrogenation of spermidine, (b) transfer of the 4-aminobutylidene group from dehydrospermidine to putrescine and (c) reduction of the imine intermediate to form homospermidine. This enzyme is more specific than EC 2.5.1.44, homospermidine synthase, which is found in bacteria, as it cannot use putrescine as donor of the 4-aminobutyl group. Forms part of the biosynthetic pathway of the poisonous pyrrolizidine alkaloids of the ragworts (Senecio).
Form
Liquid or lyophilized powder
Enzyme Commission Number
Storage
Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC.
Reaction
spermidine + putrescine = sym-homospermidine + propane-1,3-diamine
Notes
This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
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