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homospermidine synthase

Cat No.
EXWM-2780
Description
The reaction of this enzyme occurs in three steps, with some of the intermediates presumably remaining enzyme-bound: NAD+-dependent dehydrogenation of putrescine, transfer of the 4-aminobutylidene group from dehydroputrescine to a second molecule of putrescine and reduction of the imine intermediate to form homospermidine. Hence the overall reaction is transfer of a 4-aminobutyl group. Differs from EC 2.5.1.45, homospermidine synthase (spermidine-specific), which cannot use putrescine as donor of the aminobutyl group.
Form
Liquid or lyophilized powder
Enzyme Commission Number
CAS No.
76106-84-8
Storage
Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC.
Reaction
(1) 2 putrescine = sym-homospermidine + NH3 + H+; (2) putrescine + spermidine = sym-homospermidine + propane-1,3-diamine
Notes
This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
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