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Iniparib

Cat No.
CEI-0978
Description
Iniparib, also known as BSI-201, is a potent inhibitor of poly (ADP-ribose) polymerase-1 (PARP1). PARP1 plays an important role in the repair of DNA damage in cells that occurs naturally or that is induced by DNA-damaging chemotherapy. Iniparib exhibits significant antitumor activity in vitro and in vivo, either alone or in combination with chemotherapy in preclinical studies.
Abbr
Iniparib
Appearance
Yellow solid
CAS No.
160003-66-7
Molecular Weight
292 Da
Purity
>99%
Stability
Store at or below –20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.
Synonyms
BSI-201, IND-71677, 4-Iodo-3-nitrobenzamide
Targets
PARP1
Molecular Formula
C7H5IN2O3
Solubility
Soluble in DMSO at 200 mg/ml; soluble in ethanol at 12 mg/ml with warming; very poorly soluble in water; maximum solubility in plain water is estimated to be about 10-20 µM; buffers, serum, or other additives may increase or decrease the aqueous solubility.
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