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interstitial collagenase

Cat No.
EXWM-4353
Description
The enzyme takes its name from substrates of the interstitial collagen group - types I, II and III, all of which are cleaved in the helical domain. However, α-macroglobulins are cleaved much more rapidly. The enzyme is widely distributed in vertebrate animals. Type example of peptidase family M10
Form
Liquid or lyophilized powder
Enzyme Commission Number
CAS No.
9001-12-1
Storage
Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC.
Synonyms
vertebrate collagenase; matrix metalloproteinase 1
Reaction
Cleavage of the triple helix of collagen at about three-quarters of the length of the molecule from the N-terminus, at Gly775┼Ile in the α1(I) chain. Cleaves synthetic substrates and α-macroglobulins at bonds where P1' is a hydrophobic residue
Notes
This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
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