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MK-8033
Cat No.
CEI-1432
Product Overview
MK-8033 is a c-MET inhibitor in clinical trials. MK8033 is a selective small-molecule inhibitor, ATP competitive. Phase I investigation of the cMet inhibitor MK-8033 is ongoing. Plans include a trial of this agent in refractory colorectal cancer, with pre-and post-treatment biopsies to evaluate for relevant molecular signatures.
CAS No.
1001917-37-8
Molecular Weight
471.53
Storage
Store at -20°C
Synonyms
MK 8033; MK8033
Targets
C-MET
Molecular Formula
C25H21N5O3S
Chemical Name
1-[2-(1-methylpyrazol-4-yl)-11-oxobenzo[1,2]cyclohepta[2,4-b]pyridin-9-yl]-N-(pyridin-2-ylmethyl)methanesulfonamide
Solubility
DMSO
Shipping Conditions
Evaluation sample solution: ship with blue ice. All other available size: ship with RT, or blue ice upon request
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