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Enzymes for Research, Diagnostic and Industrial Use

Merck-22-6

Cat No.
CEI-1124
Description
Merck-22-6 is a potent, allosteric dual Akt1, Akt2 inhibitor with IC50=138nM and 212nM respectively. Selective over Akt3, IC50=7200nM.
Abbr
Merck-22-6(AKT1, AKT2, AKT3)
Alias
AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA
Product Overview
Akt1, Akt2 inhibitors
CAS No.
12847-42-4
Molecular Weight
653.82
Purity
> 95%
Stability
2 years -20 centigrade Powder
1 month -4 centigrade in DMSO
More than one month -80 centigrade in DMSO
Storage
4 centigrade
Synonyms
AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA
Targets
Akt1, Akt2, Akt3
IC50
138nM, 212nM, 7200nM
Molecular Formula
C40H43N7O2
Chemical Name
N-(2-(diethylamino)ethyl)-3-(4-((4-(2-oxo-2,3-dihydro-benzo[d]imidazol-1-yl)piperidin-1-yl)methyl)phenyl)-2-phenylquinoxaline-6-carboxamide
Solubility
DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL
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