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Enzymes for Research, Diagnostic and Industrial Use

Mubritinib(TAK 165)

Cat No.
CEI-0033
Description
Mubritinib(TAK 165)
Alias
TAK 165, TAK165
CAS No.
366017-09-6
Molecular Weight
468.47
Purity
>99%
Storage
2 years at -20 centigrade
Synonyms
TAK 165, TAK165
Targets
ErbB2
Molecular Formula
C25H23F3N4O2
Solubility
No
In vitro
TAK-165 can inhibit HT1376, UMUC3, T24 (bladder), ACHN (kidney), DU145, LNCaP, LN-REC4 (prostate) cell lines, which are observed HER2 expression, with IC50 from 0.09 to greater than 25 micromol/L. The prostate cancer cell lines are all sensitive to mubritinib (TAK 165).Mubritinib (TAK 165) can inhibit prostate cancer cell lines with IC50 from 0.053to 4.62 micromol/L.
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