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Native Electrophorus electricus (electric eel) Acetylcholinesterase

Cat No.
NATE-0018
Description
Acetylcholinesterase, also known as AChE or acetylhydrolase, is a hydrolase that hydrolyzes the neurotransmitter acetylcholine. AChE is found at mainly neuromuscular junctions and cholinergic brain synapses, where its activity serves to terminate synaptic transmission. It belongs to carboxylesterase family of enzymes. It is the primary target of inhibition by organophosphorus compounds such as nerve agents and pesticides.
Abbr
AChE, Native (Electrophorus electricus (electric eel))
Alias
AChE; AcCholE; Acetyl
Source
Electrophorus electricus (electric eel)
Applications
The enzyme has been used as a reference to to evaluate the effect of aspartame metabolites on hippocampal acetylcholinesterase activity. The enzyme has also been used in immobilization studies for the rapid detection of acetylthiocholine chloride.
Product Overview
Type VI-S, lyophilized powder, 200-1000 units/mg protein; Type V-S, lyophilized powder, > 1000 units/mg protein
Form
lyophilized powder
Enzyme Commission Number
EC 3.1.1.7
Activity
> 1 ,000 units/mg protein; 200-1 ,000 units/mg protein
CAS No.
9000-81-1
Molecular Weight
280 kDa
Isoelectric point
~5.3
Unit Definition
One unit will hydrolyze 1.0 μmole of acetylcholine to choline and acetate per min at pH 8.0 at 37°C.
Storage
−20°C
Buffer
Tris buffer: soluble 1 mg/mL (0.02 M Tris buffer, pH 7.5)
Synonyms
true cholinesterase; choline esterase I; cholinesterase; acetylthiocholinesterase; acetylcholine hydrolase; acetyl; β-methylcholinesterase; AcCholE; EC 3.1.1.7; 9000-81-1; Acetylcholinesterase; AChE; acetylhydrolase
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EC No.EC 3.1.1.7
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Price
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CAS No.1866-15-5
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CatalogCSUB-0003
ProductNameMATP+
EC No.
CAS No.1242026-53-4
Source
Realted Service
Realted Protocols
cholinesterase-acetyl -Enzymatic Assay Protocol
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