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Native Human Cathepsin D

Cat No.
NATE-1874
Description
Cathepsin D is an endosomal-lysosomal aspartic protease implicated in breast cancer metastasis and Alzheimer’s disease. Lysosomal release of cathepsin D has been found to precede cytochrome c release and loss of membrane potential in apoptotic human foreskin fibroblasts. Cathepsin D levels in PC12 cells increase 12 to 24 hours after apoptosis is induced.
Source
Human Spleen
Species
Human
Form
Freeze-dried powder
Enzyme Commission Number
EC 3.4.23.5
Activity
120 U/mg protein
CAS No.
9025-26-7
Purity
40% (biuret)
Storage
Store at -20° C
Synonyms
CTSD; cathepsin D; CLN10; CPSD; HEL-S-130P; EC 3.4.23.5; 9025-26-7
Solubility
Distilled water or dilute buffer
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Related Protocols
CATHEPSIN D -Enzymatic Assay Protocol
CATHEPSIN D -Enzymatic Assay Protocol
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