Products

Enzymes for Research, Diagnostic and Industrial Use

Native Vibrio cholerae Neuraminidase

Cat No.
NATE-0481
Description
Neuraminidase enzymes are glycoside hydrolase enzymes (EC 3.2.1.18) that cleave the glycosidic linkages of neuraminic acids. Neuraminidase enzymes are a large family, found in a range of organisms. The best-known neuraminidase is the viral neuraminidase, a drug target for the prevention of the spread of influenza infection. The viral neuraminidases are frequently used as antigenic determinants found on the surface of the Influenza virus. Some variants of the influenza neuraminidase confer more virulence to the virus than others. Other homologs are found in mammalian cells, which have a range of functions. At least four mammalian sialidase homologs have been described in the human genome (see NEU1, NEU2, NEU3, NEU4).
Abbr
Neuraminidase, Native (Vibrio cholerae)
Alias
sialidase
Source
Vibrio cholerae
Applications
Neurminidase is used as a cell-surface probe for glyc oconjugate distribution and in substrate specificity studies. Neuraminidase from Vibrio cholerae has been used in a study to assess its role in the binding and uptake of cholera toxin by susceptible cells. It has also been used in a study to investigate the preparation of a sodium substrate and its use in a fluorometric assay of neuraminidase.
Product Overview
Neuraminidase enzymes are glycoside hydrolase enzymes that catalyze hydrolysis of terminal sialic acid residues. The most well-known are the viral nearamidases, which promote influenza virus release.
Form
Type I, buffered aqueous solution; Aqueous solution, pH 5.5, containing 0.15 M NaCl and 4 mM CaCl2; Type II, buffered aqueous solution, Solution in 50 mM sodium acetate, pH 5.5, containing 0.15 M sodium chloride and 4 mM calcium chloride; Type III, sterile filtered, aqueous solution, pH 5.5, 0.15 M NaCl and 4 mM CaCl2.
Enzyme Commission Number
EC 3.2.1.18
Activity
Type I, 1-5 units/mg protein (Lowry, using NAN-lactose); Type II, 8-24 units/mg protein (Lowry, using NAN-lactose); Type III, > 1.5 units/mg protein.
CAS No.
9001-67-6
Unit Definition
One unit will liberate 1.0 μmole of N-acetylneuraminic acid per min at pH 5.0 at 37°C using NAN-lactose or bovine submaxillary mucin, unless otherwise specified. Prices based on units using NAN-lactose as substrate.
Storage
2-8°C
Warnings
Chromatographically purified.
Pathway
Other glycan degradation, organism-specific biosystem (from KEGG) Other glycan degradation, conserved biosystem (from KEGG) Vibrio cholerae infection, organism-specific biosystem (from KEGG) Vibrio cholerae infection, conserved biosystem (from KEGG)
Synonyms
neuraminidase; sialidase; α-neuraminidase; acetylneuraminidase; exo-α-sialidase; EC 3.2.1.18; 9001-67-6
Download Datasheet:


“Neuraminidase” Total Products Page

Inquiry
Realted Products
Catalog
ProductName
EC No.
CAS No.
Source
Price
CatalogNATE-0480
EC No.EC 3.2.1.18
CAS No.
SourceClostridium perfringens (C. welchii)
CatalogNATE-1125
EC No.EC 3.2.1.18
CAS No.9001-67-6
SourceSalmonella typhimurium
CatalogNATE-1511
EC No.EC 3.2.1.18
CAS No.9001-67-6
SourceE. coli
CatalogNATE-1512
EC No.EC 3.2.1.18
CAS No.9001-67-6
SourceE. coli
+ See More >>
Catalog
ProductName
EC No.
CAS No.
Source
Price
CatalogCSUB-0378
EC No.
CAS No.76204-02-9(anhydrous)
Source
CatalogCSUB-0379
EC No.
CAS No.26112-88-9
Source
CatalogCSUB-0380
EC No.
CAS No.76204-02-9(anhydrous)
Source
CatalogCSUB-0381
EC No.
CAS No.160369-85-7
Source
+ See More >>
Realted Protocols
neuraminidase -Enzymatic Assay Protocol
Online Inquiry
Name:
*Phone:
*E-mail Address:
Country:
Company/Institution:
*Products or Services Interested:
Quantity:
Project Description:
Our Products are Not Intended for Private Therapeutic Use!
*Verification Code:
Please input "enzymes"(case insensitive) as verification code.

Welcome! For price inquiries, please feel free to contact us through the form below through the form on the left side. We will get back to you as soon as possible.

Sitemap  Privacy Policy
Copyright ©2011 - 2017 Creative Enzymes.
Contact Us 45-1 Ramsey Road, Shirley, NY 11967, USA
Email: info@creative-enzymes.com
Tel: 1-631-562-8517 1-631-448-7888
Fax: 1-631-938-8127
Distributors To view the contact information for a specific location, select the desired country: