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PAP-1

Cat No.
CEI-1461
Product Overview
PAP-1 is selective inhibitor of Kv1.3, voltage-gated K+ channel. PAP-1 (EC50=2 nM) potently inhibits human T effector memory cell proliferation and delayed hypersensitivity. Effective orally or intraperitoneally. 5-(4-Phenoxybutoxy)psoralen has 23-fold selectivity for Kv1.3 over Kv1.5, and 33-125-fold selectivity over other Kv1 family channels.
CAS No.
870653-45-5
Molecular Weight
350.37
Purity
0.98
Storage
Store at -20°C
Synonyms
5-(4-Phenoxybutoxy)psoralen; PAP 1; PAP1
Targets
Kv1.3
Molecular Formula
C21H18O5
Chemical Name
4-(4-phenoxybutoxy)furo[3,2-g]chromen-7-one
Solubility
Soluble in DMSO
Shipping Conditions
Evaluation sample solution: ship with blue ice. All other available size: ship with RT, or blue ice upon request
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