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Enzymes for Research, Diagnostic and Industrial Use

PF-562271

Cat No.
CEI-1102
Description
PF-562271 is a potent, ATP-competitive, reversible inhibitor of FAK and Pyk2 with IC50 values of 1.5 and 14 nmol/L respectively.
Abbr
PF-562271(PTK2, RTKs, PTK2B)
Alias
FADK, FAK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK
Product Overview
Inhibitor of FAK and Pyk2
CAS No.
717907-75-0
Molecular Weight
507.5
Purity
> 95%
Stability
2 years -20 centigrade Powder
1 month -4 centigrade in DMSO
More than one month -80 centigrade in DMSO
Storage
4 centigrade
Synonyms
FADK, FAK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK
Targets
FAK, RTKs, PYK2
IC50
1.5nmol/L, 14 nmol/L
Molecular Formula
C21H20F3N7O3S
Chemical Name
N-Methyl-N-[3-[[[2-[(2-oxo-2,3-dihydro-1H-indol-5-yl)amino]-5-trifluoromethylpyrimidin-4-yl]amino]methyl]pyridin-2-yl]methanesulfonamide
Solubility
DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL
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