Products

Enzymes for Research, Diagnostic and Industrial Use

Palomid 529 (P529)

Cat No.
CEI-0084
Description
Palomid 529 inhibits both VEGF-driven and bFGF-driven endothelial cell proliferation with IC50 of 20 nM and 30 nM.
Alias
P529
CAS No.
914913-88-5
Molecular Weight
406.43
Purity
>99%
Storage
2 years at -20 centigrade
Synonyms
P529
Targets
VEGF-A, bFGF
Molecular Formula
C24H22O6
Chemical Name
3-(4-methoxybenzyloxy)-8-(1-hydroxyethyl)-2-methoxy-6H-benzo[c]chromen-6-one
Solubility
DSMO 81 mg/mL Water
In vitro
Palomid 529 inhibits proliferation and increases apoptosis of endothelial cells. Palomid 529 shows a potent antiproliferative activity in the NCI-60 cell lines panel, with growth inhibitory 50 (GI50)
In vivo
Palomid 529 shows a dose-dependent inhibition of the Ad-VEGF-A-driven angiogenesis following Palomid 529 treatment. Palomid 529 decreases AktS473 but not AktT308 signaling. Palomid 529 inhibits tumor growth, angiogenesis, and vascular permeability.
Download Datasheet:



Inquiry
Realted Products
Catalog
ProductName
EC No.
CAS No.
Source
Price
CatalogCEI-0953
ProductNameAAL-993
EC No.
CAS No.269390-77-4
Source
Online Inquiry
Name:
*Phone:
*E-mail Address:
Country:
Company/Institution:
*Products or Services Interested:
Quantity:
Project Description:
Our Products are Not Intended for Private Therapeutic Use!
*Verification Code:
Please input "enzymes"(case insensitive) as verification code.

Welcome! For price inquiries, please feel free to contact us through the form below through the form on the left side. We will get back to you as soon as possible.

Sitemap  Privacy Policy
Copyright ©2011 - 2017 Creative Enzymes.
Contact Us 45-1 Ramsey Road, Shirley, NY 11967, USA
Email: info@creative-enzymes.com
Tel: 1-631-562-8517 1-631-448-7888
Fax: 1-631-938-8127
Distributors To view the contact information for a specific location, select the desired country: