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Pimobendan (Vetmedin)
Cat No.
CEI-0250
Description
Pimobendan (Vetmedin)
Alias
Acardi, pimobendane
CAS No.
"74150-27-9
Molecular Weight
334.37
Purity
>99%
Storage
2 years at -20 centigrade
Synonyms
Acardi, pimobendane
Targets
phosphodiesterase III
Molecular Formula
C19H18N4O2
Solubility
No
In vitro
Pimobendan can selectively inhibit PDE3 with IC50 of 320 nM. Pimobendan inhibits the activity of cAMP-PDE III with IC50 of 2.4 uM. It also exerts concentration-dependent positive inotropic effects in isolated guinea-pig papillary muscles with a potency (EC50) of 6.0 uM, which is partly due to selective cardiac PDE III inhibition.
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