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tryptophan 2,3-dioxygenase

Cat No.
EXWM-0531
Description
A protohemoprotein. In mammals, the enzyme appears to be located only in the liver. This enzyme, together with EC 1.13.11.52, indoleamine 2,3-dioxygenase, catalyses the first and rate-limiting step in the kynurenine pathway, the major pathway of tryptophan metabolism. The enzyme is specific for tryptophan as substrate, but is far more active with L-tryptophan than with D-tryptophan.
Form
Liquid or lyophilized powder
Enzyme Commission Number
CAS No.
9014-51-1
Storage
Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC.
Synonyms
tryptophan pyrrolase (ambiguous); tryptophanase; tryptophan oxygenase; tryptamine 2,3-dioxygenase; tryptophan peroxidase; indoleamine 2,3-dioxygenase (ambiguous); indolamine 2,3-dioxygenase (ambiguous); L-tryptophan pyrrolase; TDO; L-tryptophan 2,3-dioxygenase; L-tryptophan:oxygen 2,3-oxidoreductase (decyclizing)
Reaction
L-tryptophan + O2 = N-formyl-L-kynurenine
Notes
This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
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