Description
Coenzyme A (CoA, CoASH, or HSCoA) is a coenzyme, notable for its role in the synthesis and oxidation of fatty acids, and the oxidation of pyruvate in the citric acid cycle. All genomes sequenced to date encode enzymes that use coenzyme A as a substrate, and around 4% of cellular enzymes use it (or a thioester, such as acetyl-CoA) as a substrate. In humans, CoA biosynthesis requires cysteine, pantothenate, and adenosine triphosphate (ATP).
Abbr
CoA-Li, Native (Yeast)
Purity
Determined by enzyme analysis with PTA* (> 75%) *PTA = Phosphotrasacetylase (LM) (EC 2.3.1.8.)
Structure
C21H27N7O14P2.Na
Specificity
Water content: < 8% by Karl Fischer
Storage
Keep tightly stoppered in the dark below 5°C. For Prolonged storage, keep below-20°C.
Synonyms
Coenzyme A, Trilithium Salt; CoA-Li; 18439-24-2