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Kallikrein

Official Full Name
Kallikrein
Background
Kallikreins are serine protease enzymes having various physiological functions. Kallikreins are implicated in carcinogenesis and have potenital as novel cancer disease biomarkers. KLK1 is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. KLK1 is functionally conserved in its ability to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen. Human Kallikrein-1, also called as Kallidinogenase, Kininogenase or Kininogenin, is an active protein enzyme present in saliva, pancreatic juices, and urine that catalyzes the proteolysis of bradykininogen to bradykinin. Kallikrein-1, which derived from human or porcine, have been used as drugs for a long time, they are mainly used in the treatment f light to medium hypertension and occlusion of cerebral and surrounding blood vessels.
Synonyms
KLK1; KLK-1; HK1; HK-1; KLKR; KLK6; Tissue Kallikrein; Hklk1; EC 3.4.21.35; Kidney/pancreas/salivary gland kallikrein; Kallikrein-1

Catalog
ProductName
EC No.
CAS No.
Source
Price
CatalogEXWM-4128
EC No.EC 3.4.21.34
CAS No.410538-33-9
Source
CatalogNATE-0851
EC No.
CAS No.
SourcePichia Pastoris
CatalogNATE-0362
EC No.EC 3.4.21.35
CAS No.9001-01-8
SourcePorcine pancrea...
CatalogNATE-0361
EC No.EC 3.4.21.34
CAS No.9001-01-8
SourceHuman plasma
Related Protocols
KALLIKREIN from Human Plasma -Enzymatic Assay Protocol
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