Native Bovine Ribonuclease B

Cat No.

NATE-0656

Description

Native RNase BS generated by subtilisin digestion of native RNase B comprising of amino acid residues 21-124 of RNase B, is sensitive to PNGase F digestion. Intramolecular N-glycans of bovine pancreatic RNase B function like chaperone. RNase B is found to be much faster than RNase A, while RNase A is liable to aggregate during regeneration. The stimulatory effect of Asn-oligosaccharide (which corresponds to the most predominant sugar chain of RNase B) reveals that the N-glycans of RNase B facilitates the transformation of bulky intermediates into folded, compact species.

Abbr

RNase B, Native (Bovine)

Alias

RNase B

Source

Bovine pancreas

Species

Bovine

Package

Package size based on protein content

Enzyme Commission Number

EC 3.1.27.5

Activity

> 50 Kunitz units/mg protein

CAS No.

9001-99-4

Purity

> 80% (SDS-PAGE)

Storage

−20°C

Warnings

Derived from New Zealand-sourced pancreas. Purified by affinity chromatography.

Synonyms

Pancreatic ribonucleases; EC 3.1.27.5; RNase; RNase I; RNase B; pancreatic RNase; ribonuclease I; endoribonuclease I; ribonucleic phosphatase; alkaline ribonuclease; ribonuclease; gene S glycoproteins; Ceratitis capitata alkaline ribonuclease; SLSG glycoproteins; gene S locus-specific glycoproteins; S-genotype-asssocd. glycoproteins; ribonucleate 3'-pyrimidino-oligonucleotidohydrolase; 9001-99-4

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