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Phosphodiesterase 2A active from Rat, Recombinant

Cat No.
NATE-0520
Description
cGMP-dependent 3',5'-cyclic phosphodiesterase is an enzyme that in humans is encoded by the PDE2A gene.
Abbr
PDE2A, Recombinant (Rat)
Alias
PDE2A; PDE2A1; PED2A4; cGSPDE
Source
Baculovirus infected Sf9 cells
Species
Rat
Product Overview
Rat PDE2A (GenBank Accession No. NM_00143847) full length with N-terminal His-GST-tag, MW=133 kDa, expressed in a Baculovirus infected Sf9 cell expression system
Form
aqueous solution
Molecular Weight
mol wt 133 kDa
Purity
> 56% (SDS-PAGE)
Storage
−70°C
Pathway
G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; Hemostasis, organism-specific biosystem; Morphine addiction, organism-specific biosystem; Morphine addiction, conserved biosystem; Nitric oxide stimulates guanylate cyclase, organism-specific biosystem; Platelet homeostasis, organism-specific biosystem
Function
3,5-cyclic-nucleotide phosphodiesterase activity; TPR domain binding; cAMP binding; cGMP binding; cGMP binding; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity; calcium channel activity; cyclic-nucleotide phosphodiesterase activity; drug binding; drug binding; hydrolase activity; metal ion binding; nucleotide binding; phosphoric diester hydrolase activity; protein binding; protein homodimerization activity
Synonyms
PDE2A; phosphodiesterase 2A, cGMP-stimulated; CGS-PDE; PDE2A1; PED2A4; cGSPDE
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